ARCHETYPE TestMicroscopic findings - Breast cancer (openEHR-EHR-CLUSTER.testmicroscopy_breast_carcinoma.v1)

ARCHETYPE IDopenEHR-EHR-CLUSTER.testmicroscopy_breast_carcinoma.v1
ConceptTestMicroscopic findings - Breast cancer
DescriptionMicroscopic anatomic pathology findings related to breast cancer.
UseTo record detailed findings about microscopic examination of tissue related to breast cancer. Use as a component archetype in the context of a suite of archetypes that make up a histopathology report ie OBSERVATION.lab_test.histopathology.
MisuseNot designed to be used within any other archetype other than OBSERVATION.lab_test.histopathology.
PurposeTo record detailed findings about breast cancer found on microscopic examination.
ReferencesThe Royal College of Pathologists, NHS Cancer Screening Programmes. Pathology Reporting of Breast Disease [Internet]. 2005 Jan ;[cited 2009 Jul 26]
Available from: http://www.rcpath.org/resources/pdf/PathologyReportingOfBreastDisease-CORRECTED-lowres.pdf

British Columbia Cancer Agency. Synoptic Report Form for Breast Cancer [Internet]. 2005 Dec 13;[cited 2009 Jul 26 ] Available from: http://www.bccancer.bc.ca/HPI/CancerManagementGuidelines/Breast/Management/SynopticReportForm1of6/default.htm



Copyrightcopyright (c) 2011 openEHR Foundation
AuthorsAuthor name: Dr Ian McNicoll
Organisation: Ocean Informatics, UK
Email: ian.mcnicoll@oceaninformatics.com
Date originally authored: 17/06/2009
Other Details LanguageAuthor name: Dr Ian McNicoll
Organisation: Ocean Informatics, UK
Email: ian.mcnicoll@oceaninformatics.com
Date originally authored: 17/06/2009
OtherDetails Language Independent{references=The Royal College of Pathologists, NHS Cancer Screening Programmes. Pathology Reporting of Breast Disease [Internet]. 2005 Jan ;[cited 2009 Jul 26] Available from: http://www.rcpath.org/resources/pdf/PathologyReportingOfBreastDisease-CORRECTED-lowres.pdf British Columbia Cancer Agency. Synoptic Report Form for Breast Cancer [Internet]. 2005 Dec 13;[cited 2009 Jul 26 ] Available from: http://www.bccancer.bc.ca/HPI/CancerManagementGuidelines/Breast/Management/SynopticReportForm1of6/default.htm , MD5-CAM-1.0.1=C234E5A033F8C31D22E8DA49BCA51C40}
Keywordsbreast, histopathology, cancer, laboratory, lab, pathology, histology, malignancy
LifecycleInitial
Language useden
Citeable Identifier1013.1.820
AllArchetype [runtimeNameConstraintForConceptName=null, archetypeConceptBinding=null, archetypeConceptDescription=Microscopic anatomic pathology findings related to breast cancer., archetypeConceptComment=null, otherContributors=David Rowed, Ocean Informatics, Australia
Heather Leslie, Ocean Informatics, Australia
Cathy Richardson, NEHTA, Australia
David McKillop, NEHTA, Australia
Koray Atalag, University of Auckland, New Zealand
Matt Cordell, NEHTA, Australia, originalLanguage=en, translators=, subjectOfData=unconstrained, archetypeTranslationTree=null, topLevelToAshis={events=[], context=[], capabilities=[], activities=[], protocol=[], identities=[], source=[], credentials=[], state=[], items=[ResourceSimplifiedHierarchyItem [path=/items[at0033], code=at0033, itemType=CLUSTER, level=1, text=Tumour size and extent, description=Assessments of tumour size., comment=null, uncommonOntologyItems=null, occurencesFormal=0..*, occurencesText=Optional, repeating, cardinalityFormal=1..*, cardinalityText=, subCardinalityFormal=null, subCardinalityText=null, dataType=CLUSTER, bindings=null, values=, extendedValues=null], ResourceSimplifiedHierarchyItem [path=/items[at0033]/items[at0036], code=at0036, itemType=SLOT, level=2, text=Invasive tumour extent, description=The size of the invasive aspect of the breast cancer., comment=null, uncommonOntologyItems=null, occurencesFormal=0..*, occurencesText=Optional, repeating, cardinalityFormal=null, cardinalityText=null, subCardinalityFormal=null, subCardinalityText=null, dataType=CLUSTER, bindings=null, values=Include:
openEHR-EHR-CLUSTER.physical_properties.v1
Exclude:
All not explicitly included archetypes, extendedValues=null], ResourceSimplifiedHierarchyItem [path=/items[at0033]/items[at0037], code=at0037, itemType=SLOT, level=2, text=Total lesion extent, description=The extent of total breast cancer lesion., comment=null, uncommonOntologyItems=null, occurencesFormal=0..*, occurencesText=Optional, repeating, cardinalityFormal=null, cardinalityText=null, subCardinalityFormal=null, subCardinalityText=null, dataType=CLUSTER, bindings=null, values=Include:
openEHR-EHR-CLUSTER.physical_properties.v1
Exclude:
All not explicitly included archetypes, extendedValues=null], ResourceSimplifiedHierarchyItem [path=/items[at0015], code=at0015, itemType=CLUSTER, level=1, text=Histologic grading, description=Histologic grading of breast cancer., comment=null, uncommonOntologyItems=null, occurencesFormal=0..1, occurencesText=Optional, cardinalityFormal=1..*, cardinalityText=, subCardinalityFormal=null, subCardinalityText=null, dataType=CLUSTER, bindings=null, values=, extendedValues=null], ResourceSimplifiedHierarchyItem [path=/items[at0015]/items[at0020], code=at0020, itemType=CLUSTER, level=2, text=Bloom and Richardson Grade, description=Bloom and Richardson Histology Grade ( with modification by Elston and Ellis) is composed of three components which are combined to produce a calculated Histology Grade., comment=null, uncommonOntologyItems=null, occurencesFormal=0..1, occurencesText=Optional, cardinalityFormal=1..*, cardinalityText=, subCardinalityFormal=null, subCardinalityText=null, dataType=CLUSTER, bindings=null, values=, extendedValues=null], ResourceSimplifiedHierarchyItem [path=/items[at0015]/items[at0020]/items[at0014], code=at0014, itemType=ELEMENT, level=3, text=Mitosis count, description=Mitotic frequency is calculated from the number of mitoses per 10 high-power fields., comment=null, uncommonOntologyItems=null, occurencesFormal=0..1, occurencesText=Optional, cardinalityFormal=null, cardinalityText=null, subCardinalityFormal=null, subCardinalityText=null, dataType=DV_COUNT, bindings=null, values=, extendedValues=null], ResourceSimplifiedHierarchyItem [path=/items[at0015]/items[at0020]/items[at0175], code=at0175, itemType=ELEMENT, level=3, text=Mitotic frequency score, description=Mitotic frequency score calculated from the mitosis count and the microscopy field diameter via a lookup table., comment=null, uncommonOntologyItems=null, occurencesFormal=0..1, occurencesText=Optional, cardinalityFormal=null, cardinalityText=null, subCardinalityFormal=null, subCardinalityText=null, dataType=C_DV_ORDINAL, bindings=null, values=1: Score 1 [Low mitotic frequency.]
2: Score 2 [Intermediate mitotic frequency.]
3: Score 3 [High mitotic frequency.]
, extendedValues=null], ResourceSimplifiedHierarchyItem [path=/items[at0015]/items[at0020]/items[at0016], code=at0016, itemType=ELEMENT, level=3, text=Nuclear score, description=Nuclear score., comment=null, uncommonOntologyItems=null, occurencesFormal=0..1, occurencesText=Optional, cardinalityFormal=null, cardinalityText=null, subCardinalityFormal=null, subCardinalityText=null, dataType=C_DV_ORDINAL, bindings=null, values=1: Score 1 [Size equivalent to 1.5–2 red blood cell diameters or normal duct epithelial nuclei; Diffuse chromatin; Inconspicuous nucleoli.]
2: Score 2 [Size equivalent to 2–2.5 red blood cell diameters; Coarse chromatin; Infrequent nucleoli and mitoses.]
3: Score 3 [Size > 2.5 red blood cell diameters; Pleomorphic vesicular nuclei; One or more prominent nucleoli; Frequent mitotic figures commonly present.]
, extendedValues=null], ResourceSimplifiedHierarchyItem [path=/items[at0015]/items[at0020]/items[at0017], code=at0017, itemType=ELEMENT, level=3, text=Tubular formation score, description=Tubular formation score, representing the extent of tubular formation within invasive carcinoma cells., comment=null, uncommonOntologyItems=null, occurencesFormal=0..1, occurencesText=Optional, cardinalityFormal=null, cardinalityText=null, subCardinalityFormal=null, subCardinalityText=null, dataType=C_DV_ORDINAL, bindings=null, values=1: Tubular formation score 1 [> 75% of invasive carcinoma forming tubular or glandular structures.]
2: Tubular formation score 2 [10–75% of invasive carcinoma forming tubular or glandular structures.]
3: Tubular formation score 3 [< 10% of invasive carcinoma forming tubular or glandular structures.]
, extendedValues=null], ResourceSimplifiedHierarchyItem [path=/items[at0015]/items[at0020]/items[at0018], code=at0018, itemType=ELEMENT, level=3, text=Histologic grade, description=Bloom and Richardson Grade of breast cancer, derived from the total score of its components: Mitotic frequency score, Nuclear score and Tubular formation score;, comment=null, uncommonOntologyItems=null, occurencesFormal=0..1, occurencesText=Optional, cardinalityFormal=null, cardinalityText=null, subCardinalityFormal=null, subCardinalityText=null, dataType=C_DV_ORDINAL, bindings=null, values=1: Grade 1 [Total score of 3–5.]
2: Grade 2 [Total score of 6 or 7.]
3: Grade 3 [Total score of 8 or 9.]
, extendedValues=null], ResourceSimplifiedHierarchyItem [path=/items[at0015]/items[at0020]/items[at0043], code=at0043, itemType=ELEMENT, level=3, text=Confounding issues, description=A text description of any assessment issues which may confound the accuracy of the Bloom and Richardson histologic grade., comment=null, uncommonOntologyItems=null, occurencesFormal=0..1, occurencesText=Optional, cardinalityFormal=null, cardinalityText=null, subCardinalityFormal=null, subCardinalityText=null, dataType=DV_TEXT, bindings=null, values=, extendedValues=null], ResourceSimplifiedHierarchyItem [path=/items[at0161], code=at0161, itemType=CLUSTER, level=1, text=Local tumour invasion, description=Findings of local tumour invasion., comment=null, uncommonOntologyItems=null, occurencesFormal=0..1, occurencesText=Optional, cardinalityFormal=1..*, cardinalityText=, subCardinalityFormal=null, subCardinalityText=null, dataType=CLUSTER, bindings=null, values=, extendedValues=null], ResourceSimplifiedHierarchyItem [path=/items[at0161]/items[at0159], code=at0159, itemType=SLOT, level=2, text=Lymphovascular invasion, description=Details of local invasion into lymphovascular tissue., comment=null, uncommonOntologyItems=null, occurencesFormal=0..1, occurencesText=Optional, cardinalityFormal=null, cardinalityText=null, subCardinalityFormal=null, subCardinalityText=null, dataType=CLUSTER, bindings=null, values=Include:
All not explicitly excluded archetypes
Exclude:
openEHR-EHR-CLUSTER.tumour_invasion.v1, extendedValues=null], ResourceSimplifiedHierarchyItem [path=/items[at0161]/items[at0160], code=at0160, itemType=SLOT, level=2, text=Skin / muscle invasion, description=Details of local invasion into skin or muscle tissue., comment=null, uncommonOntologyItems=null, occurencesFormal=0..1, occurencesText=Optional, cardinalityFormal=null, cardinalityText=null, subCardinalityFormal=null, subCardinalityText=null, dataType=CLUSTER, bindings=null, values=Include:
openEHR-EHR-CLUSTER.tumour_invasion.v1
Exclude:
All not explicitly included archetypes, extendedValues=null], ResourceSimplifiedHierarchyItem [path=/items[at0021], code=at0021, itemType=CLUSTER, level=1, text=Resection margins, description=Findings of the relation of tumour to surgical resection margins., comment=null, uncommonOntologyItems=null, occurencesFormal=0..1, occurencesText=Optional, cardinalityFormal=1..*, cardinalityText=, subCardinalityFormal=null, subCardinalityText=null, dataType=CLUSTER, bindings=null, values=, extendedValues=null], ResourceSimplifiedHierarchyItem [path=/items[at0021]/items[at0084], code=at0084, itemType=SLOT, level=2, text=Invasive carcinoma at margin, description=Details of invasive carcinoma at surgical resection margins., comment=null, uncommonOntologyItems=null, occurencesFormal=0..1, occurencesText=Optional, cardinalityFormal=null, cardinalityText=null, subCardinalityFormal=null, subCardinalityText=null, dataType=CLUSTER, bindings=null, values=Include:
openEHR-EHR-CLUSTER.tumour_resection_margins.v1
Exclude:
All not explicitly included archetypes, extendedValues=null], ResourceSimplifiedHierarchyItem [path=/items[at0021]/items[at0113], code=at0113, itemType=SLOT, level=2, text=DCIS at margin, description=Details of DCIS (Ductal carcinoma-in-situ) at surgical resection margins., comment=null, uncommonOntologyItems=null, occurencesFormal=0..1, occurencesText=Optional, cardinalityFormal=null, cardinalityText=null, subCardinalityFormal=null, subCardinalityText=null, dataType=CLUSTER, bindings=null, values=Include:
openEHR-EHR-CLUSTER.tumour_resection_margins.v1
Exclude:
All not explicitly included archetypes, extendedValues=null], ResourceSimplifiedHierarchyItem [path=/items[at0021]/items[at0115], code=at0115, itemType=SLOT, level=2, text=LCIS at margin, description=Details of LCIS (Local carcinoma-in-situ) at surgical resection margins., comment=null, uncommonOntologyItems=null, occurencesFormal=0..1, occurencesText=Optional, cardinalityFormal=null, cardinalityText=null, subCardinalityFormal=null, subCardinalityText=null, dataType=CLUSTER, bindings=null, values=Include:
openEHR-EHR-CLUSTER.tumour_resection_margins.v1
Exclude:
All not explicitly included archetypes, extendedValues=null], ResourceSimplifiedHierarchyItem [path=/items[at0054], code=at0054, itemType=CLUSTER, level=1, text=Non-neoplastic cellular changes, description=Findings of non-neoplastic cellular changes., comment=null, uncommonOntologyItems=null, occurencesFormal=0..1, occurencesText=Optional, cardinalityFormal=1..*, cardinalityText=, subCardinalityFormal=null, subCardinalityText=null, dataType=CLUSTER, bindings=null, values=, extendedValues=null], ResourceSimplifiedHierarchyItem [path=/items[at0054]/items[at0023], code=at0023, itemType=ELEMENT, level=2, text=Non-neoplastic cellular change, description=Finding of non-neoplastic cellular change., comment=null, uncommonOntologyItems=null, occurencesFormal=0..*, occurencesText=Optional, repeating, cardinalityFormal=null, cardinalityText=null, subCardinalityFormal=null, subCardinalityText=null, dataType=DV_TEXT, bindings=null, values=, extendedValues=null], ResourceSimplifiedHierarchyItem [path=/items[at0060], code=at0060, itemType=CLUSTER, level=1, text=Lobular neoplasia, description=Findings of lobular neoplasia and variants., comment=null, uncommonOntologyItems=null, occurencesFormal=0..1, occurencesText=Optional, cardinalityFormal=1..*, cardinalityText=, subCardinalityFormal=null, subCardinalityText=null, dataType=CLUSTER, bindings=null, values=, extendedValues=null], ResourceSimplifiedHierarchyItem [path=/items[at0060]/items[at0061], code=at0061, itemType=ELEMENT, level=2, text=Lobular neoplasia, description=Finding of lobular neoplasia., comment=null, uncommonOntologyItems=null, occurencesFormal=0..1, occurencesText=Optional, cardinalityFormal=null, cardinalityText=null, subCardinalityFormal=null, subCardinalityText=null, dataType=CHOICE, bindings=null, values=Choice of:
  •  Coded Text
    • Present - classical [Classical lobular neoplasia is present.]
    • Present - pleomorphic [Pleomorphic lobular neoplasia is present.]
    • Absent [Lobular neoplasia is absent.]
    • Indeterminate [The presence of lobular hyperplasia has not been determined.]
  •  Text
, extendedValues=null], ResourceSimplifiedHierarchyItem [path=/items[at0060]/items[at0055], code=at0055, itemType=ELEMENT, level=2, text=Atypical lobular hyperplasia, description=Finding of atypical lobular hyperplasia., comment=null, uncommonOntologyItems=null, occurencesFormal=0..1, occurencesText=Optional, cardinalityFormal=null, cardinalityText=null, subCardinalityFormal=null, subCardinalityText=null, dataType=CHOICE, bindings=null, values=Choice of:
  •  Coded Text
    • Present - classical [Classical atypical lobular neoplasia is present.]
    • Present - pleomorphic [Pleomorphic atypical lobular neoplasia is present.]
    • Absent [Atypical lobular neoplasia is absent.]
    • Indeterminate [The presence of atypical lobular neoplasia has not been determined.]
  •  Text
, extendedValues=null], ResourceSimplifiedHierarchyItem [path=/items[at0060]/items[at0058], code=at0058, itemType=ELEMENT, level=2, text=Lobular carcinoma-in-situ, description=Finding of lobular carcinoma-in-situ., comment=null, uncommonOntologyItems=null, occurencesFormal=0..1, occurencesText=Optional, cardinalityFormal=null, cardinalityText=null, subCardinalityFormal=null, subCardinalityText=null, dataType=CHOICE, bindings=null, values=Choice of:
  •  Coded Text
    • Present - classical [Classical lobular carcinoma-in-situ is present.]
    • Present - pleomorphic [Pleomorphic lobular carcinoma-in-situ is present.]
    • Absent [Lobular carcinoma-in-situ is absent.]
    • Indeterminate [The presence of lobular carcinoma-in-situ has not been determined]
  •  Text
, extendedValues=null], ResourceSimplifiedHierarchyItem [path=/items[at0060]/items[at0056], code=at0056, itemType=ELEMENT, level=2, text=Description, description=A text description of finding of lobular neoplasia., comment=null, uncommonOntologyItems=null, occurencesFormal=0..1, occurencesText=Optional, cardinalityFormal=null, cardinalityText=null, subCardinalityFormal=null, subCardinalityText=null, dataType=DV_TEXT, bindings=null, values=, extendedValues=null], ResourceSimplifiedHierarchyItem [path=/items[at0062], code=at0062, itemType=CLUSTER, level=1, text=Paget's disease of nipple, description=Findings related to Paget's disease of the nipple., comment=null, uncommonOntologyItems=null, occurencesFormal=0..1, occurencesText=Optional, cardinalityFormal=1..*, cardinalityText=, subCardinalityFormal=null, subCardinalityText=null, dataType=CLUSTER, bindings=null, values=, extendedValues=null], ResourceSimplifiedHierarchyItem [path=/items[at0062]/items[at0063], code=at0063, itemType=ELEMENT, level=2, text=Paget's disease of nipple, description=Finding of Paget's disease of the nipple., comment=null, uncommonOntologyItems=null, occurencesFormal=0..1, occurencesText=Optional, cardinalityFormal=null, cardinalityText=null, subCardinalityFormal=null, subCardinalityText=null, dataType=DV_CODED_TEXT, bindings=null, values=
  • Present [Paget's disease of the nipple is present.]
  • Absent [Paget's disease of the nipple is absent.]
  • Indeterminate [Presence of Paget's disease of the nipple has not been determined.]
, extendedValues=null], ResourceSimplifiedHierarchyItem [path=/items[at0024], code=at0024, itemType=CLUSTER, level=1, text=Microcalcification, description=Findings related to microcalcification., comment=null, uncommonOntologyItems=null, occurencesFormal=0..1, occurencesText=Optional, cardinalityFormal=1..*, cardinalityText=, subCardinalityFormal=null, subCardinalityText=null, dataType=CLUSTER, bindings=null, values=, extendedValues=null], ResourceSimplifiedHierarchyItem [path=/items[at0024]/items[at0025], code=at0025, itemType=ELEMENT, level=2, text=Microcalcification, description=Findings of microcalcification., comment=null, uncommonOntologyItems=null, occurencesFormal=0..1, occurencesText=Optional, cardinalityFormal=null, cardinalityText=null, subCardinalityFormal=null, subCardinalityText=null, dataType=DV_CODED_TEXT, bindings=null, values=
  • Present [Microcalcification is present.]
  • Absent [Microcalcification is absent.]
  • Indeterminate [Presence of microcalcification has not been determined.]
  • Present - no evidence of necrosis [Microcalcification is present with no evidence of necrosis.]
  • Present - with evidence of necrosis [Microcalcification is present with evidence of necrosis.]
, extendedValues=null], ResourceSimplifiedHierarchyItem [path=/items[at0024]/items[at0026], code=at0026, itemType=ELEMENT, level=2, text=Associated pathology, description=A text description of pathology associated with microcalcification., comment=null, uncommonOntologyItems=null, occurencesFormal=0..1, occurencesText=Optional, cardinalityFormal=null, cardinalityText=null, subCardinalityFormal=null, subCardinalityText=null, dataType=DV_TEXT, bindings=null, values=, extendedValues=null], ResourceSimplifiedHierarchyItem [path=/items[at0064], code=at0064, itemType=CLUSTER, level=1, text=DCIS features, description=Findings related to Ductal carcinoma-in-situ (DCIS)., comment=null, uncommonOntologyItems=null, occurencesFormal=0..1, occurencesText=Optional, cardinalityFormal=1..*, cardinalityText=, subCardinalityFormal=null, subCardinalityText=null, dataType=CLUSTER, bindings=null, values=, extendedValues=null], ResourceSimplifiedHierarchyItem [path=/items[at0064]/items[at0154], code=at0154, itemType=ELEMENT, level=2, text=Calcification, description=Finding of calcification in DCIS tissue., comment=null, uncommonOntologyItems=null, occurencesFormal=0..1, occurencesText=Optional, cardinalityFormal=null, cardinalityText=null, subCardinalityFormal=null, subCardinalityText=null, dataType=DV_CODED_TEXT, bindings=null, values=
  • Present with necrosis [Calcification with necrosis is present in DCIS tissue.]
  • Present without necrosis [Calcification without necrosis is present in DCIS tissue]
  • Absent [Calcification is absent from DCIS tissue.]
  • Indeterminate [Presence of calcification in DCIS tissue has not been determined.]
, extendedValues=null], ResourceSimplifiedHierarchyItem [path=/items[at0064]/items[at0125], code=at0125, itemType=CLUSTER, level=2, text=Histologic grade, description=Histologic grading of DCIS., comment=null, uncommonOntologyItems=null, occurencesFormal=0..1, occurencesText=Optional, cardinalityFormal=1..*, cardinalityText=, subCardinalityFormal=null, subCardinalityText=null, dataType=CLUSTER, bindings=null, values=, extendedValues=null], ResourceSimplifiedHierarchyItem [path=/items[at0064]/items[at0125]/items[at0075], code=at0075, itemType=ELEMENT, level=3, text=Necrosis, description=Findings of tumour necrosis., comment=null, uncommonOntologyItems=null, occurencesFormal=0..1, occurencesText=Optional, cardinalityFormal=null, cardinalityText=null, subCardinalityFormal=null, subCardinalityText=null, dataType=DV_CODED_TEXT, bindings=null, values=
  • Present (non-comedo type) [Non-comedo type of tumour necrosis is present.]
  • Present (Comedo type) [Comedo type of tumour necrosis is present.]
  • Absent or minimal [Tumour necrosis is absent or minimal.]
, extendedValues=null], ResourceSimplifiedHierarchyItem [path=/items[at0064]/items[at0125]/items[at0070], code=at0070, itemType=ELEMENT, level=3, text=Nuclear score, description=Nuclear score, using the Elston and Ellis modification of the Bloom and Richardson system for grading invasive carcinoma., comment=null, uncommonOntologyItems=null, occurencesFormal=0..1, occurencesText=Optional, cardinalityFormal=null, cardinalityText=null, subCardinalityFormal=null, subCardinalityText=null, dataType=C_DV_ORDINAL, bindings=null, values=1: Score 1 [Size equivalent to 1.5–2 red blood cell diameters or normal duct epithelial nuclei; Diffuse chromatin; Inconspicuous nucleoli.]
2: Score 2 [Size equivalent to 2–2.5 red blood cell diameters; Coarse chromatin; Infrequent nucleoli and mitoses.]
3: Score 3 [Size > 2.5 red blood cell diameters; Pleomorphic vesicular nuclei; One or more prominent nucleoli; Frequent mitotic figures commonly present.]
, extendedValues=null], ResourceSimplifiedHierarchyItem [path=/items[at0064]/items[at0125]/items[at0080], code=at0080, itemType=ELEMENT, level=3, text=Van Nuys Prognostic Index, description=The Van Nuys Prognostic Index (VNPI)., comment=null, uncommonOntologyItems=null, occurencesFormal=0..1, occurencesText=Optional, cardinalityFormal=null, cardinalityText=null, subCardinalityFormal=null, subCardinalityText=null, dataType=C_DV_ORDINAL, bindings=null, values=1: Van Nuys Group 1 [Nuclear grade 1 or 2 and no necrosis.]
2: Van Nuys Group 2 [Nuclear grade 1 or 2 and necrosis.]
3: Van Nuys Group 3 [Nuclear grade 3 with or without necrosis.]
, extendedValues=null], ResourceSimplifiedHierarchyItem [path=/items[at0064]/items[at0125]/items[at0179], code=at0179, itemType=ELEMENT, level=3, text=Comment, description=Comment on estimation of the histologic grade., comment=null, uncommonOntologyItems=null, occurencesFormal=0..1, occurencesText=Optional, cardinalityFormal=null, cardinalityText=null, subCardinalityFormal=null, subCardinalityText=null, dataType=DV_TEXT, bindings=null, values=, extendedValues=null], ResourceSimplifiedHierarchyItem [path=/items[at0064]/items[at0128], code=at0128, itemType=CLUSTER, level=2, text=DCIS Architecture, description=Findings related to architecture of the ductal carcinoma-in-situ., comment=null, uncommonOntologyItems=null, occurencesFormal=0..1, occurencesText=Optional, cardinalityFormal=1..*, cardinalityText=, subCardinalityFormal=null, subCardinalityText=null, dataType=CLUSTER, bindings=null, values=, extendedValues=null], ResourceSimplifiedHierarchyItem [path=/items[at0064]/items[at0128]/items[at0130], code=at0130, itemType=ELEMENT, level=3, text=Dominant pattern, description=Findingof the dominant DCIS architectural pattern., comment=null, uncommonOntologyItems=null, occurencesFormal=0..1, occurencesText=Optional, cardinalityFormal=null, cardinalityText=null, subCardinalityFormal=null, subCardinalityText=null, dataType=CHOICE, bindings=null, values=Choice of:
  •  Coded Text
    • Solid [Solid pattern of ductal carcinoma-in-situ.]
    • Cribriform [Cribriform pattern of ductal carcinoma-in-situ.]
    • Micropapillary [Micropapillary pattern of ductal carcinoma-in-situ.]
    • Apocrine [Apocrine pattern of ductal carcinoma-in-situ.]
    • Papillary [Papillary pattern of ductal carcinoma-in-situ.]
    • Indeterminate [The dominant pattern of ductal carcinoma-in-situ has not been determined.]
  •  Text
, extendedValues=null], ResourceSimplifiedHierarchyItem [path=/items[at0064]/items[at0128]/items[at0131], code=at0131, itemType=ELEMENT, level=3, text=Description, description=A text description of the architectural pattern., comment=null, uncommonOntologyItems=null, occurencesFormal=0..1, occurencesText=Optional, cardinalityFormal=null, cardinalityText=null, subCardinalityFormal=null, subCardinalityText=null, dataType=DV_TEXT, bindings=null, values=, extendedValues=null], ResourceSimplifiedHierarchyItem [path=/items[at0094], code=at0094, itemType=CLUSTER, level=1, text=Hormone Receptor assays, description=Immunohistochemical assays of oestrogen receptor (ER) and progesterone receptor (PR)., comment=null, uncommonOntologyItems=null, occurencesFormal=0..1, occurencesText=Optional, cardinalityFormal=1..*, cardinalityText=, subCardinalityFormal=null, subCardinalityText=null, dataType=CLUSTER, bindings=null, values=, extendedValues=null], ResourceSimplifiedHierarchyItem [path=/items[at0094]/items[at0095], code=at0095, itemType=CLUSTER, level=2, text=Oestrogen receptor assay (ER), description=Oestrogen Receptor assay (ER)., comment=null, uncommonOntologyItems=null, occurencesFormal=0..2, occurencesText=Optional, cardinalityFormal=1..*, cardinalityText=, subCardinalityFormal=null, subCardinalityText=null, dataType=CLUSTER, bindings=null, values=, extendedValues=null], ResourceSimplifiedHierarchyItem [path=/items[at0094]/items[at0095]/items[at0096], code=at0096, itemType=ELEMENT, level=3, text=ER result, description=Oestrogen Receptor assay result., comment=null, uncommonOntologyItems=null, occurencesFormal=0..1, occurencesText=Optional, cardinalityFormal=null, cardinalityText=null, subCardinalityFormal=null, subCardinalityText=null, dataType=DV_CODED_TEXT, bindings=null, values=
  • Positive [Oestrogen Receptor assay result is positive.]
  • Negative [Oestrogen Receptor assay result is negative.]
  • Equivocal [Oestrogen Receptor assay result is equivocal.]
, extendedValues=null], ResourceSimplifiedHierarchyItem [path=/items[at0094]/items[at0095]/items[at0100], code=at0100, itemType=ELEMENT, level=3, text=Proportion of nuclei stained, description=An estimate of the percentage of nuclei stained., comment=null, uncommonOntologyItems=null, occurencesFormal=0..1, occurencesText=Optional, cardinalityFormal=null, cardinalityText=null, subCardinalityFormal=null, subCardinalityText=null, dataType=DV_PROPORTION, bindings=null, values=, extendedValues=null], ResourceSimplifiedHierarchyItem [path=/items[at0094]/items[at0095]/items[at0101], code=at0101, itemType=ELEMENT, level=3, text=Predominant staining intensity, description=Predominant intensity of staining., comment=null, uncommonOntologyItems=null, occurencesFormal=0..1, occurencesText=Optional, cardinalityFormal=null, cardinalityText=null, subCardinalityFormal=null, subCardinalityText=null, dataType=DV_CODED_TEXT, bindings=null, values=
  • Low [Predominant intensity of staining is low.]
  • Intermediate [Predominant intensity of staining is intermediate.]
  • High [Predominant intensity of staining is high.]
, extendedValues=null], ResourceSimplifiedHierarchyItem [path=/items[at0094]/items[at0102], code=at0102, itemType=CLUSTER, level=2, text=Progesterone receptor assay (PR), description=Progesterone Receptor (PR) assay., comment=null, uncommonOntologyItems=null, occurencesFormal=0..1, occurencesText=Optional, cardinalityFormal=1..*, cardinalityText=, subCardinalityFormal=null, subCardinalityText=null, dataType=CLUSTER, bindings=null, values=, extendedValues=null], ResourceSimplifiedHierarchyItem [path=/items[at0094]/items[at0102]/items[at0138], code=at0138, itemType=ELEMENT, level=3, text=PR result, description=Progesterone Receptor assay result., comment=null, uncommonOntologyItems=null, occurencesFormal=0..1, occurencesText=Optional, cardinalityFormal=null, cardinalityText=null, subCardinalityFormal=null, subCardinalityText=null, dataType=DV_CODED_TEXT, bindings=null, values=
  • Positive [Progesterone Receptor assay result is positive.]
  • Negative [Progesterone Receptor assay result is negative.]
  • Equivocal [Progesterone Receptor assay result is equivocal.]
, extendedValues=null], ResourceSimplifiedHierarchyItem [path=/items[at0094]/items[at0102]/items[at0162], code=at0162, itemType=ELEMENT, level=3, text=Proportion of nuclei stained, description=An estimate of the percentage of nuclei stained., comment=null, uncommonOntologyItems=null, occurencesFormal=0..1, occurencesText=Optional, cardinalityFormal=null, cardinalityText=null, subCardinalityFormal=null, subCardinalityText=null, dataType=DV_PROPORTION, bindings=null, values=, extendedValues=null], ResourceSimplifiedHierarchyItem [path=/items[at0094]/items[at0102]/items[at0163], code=at0163, itemType=ELEMENT, level=3, text=Predominant staining intensity, description=Predominant intensity of staining., comment=null, uncommonOntologyItems=null, occurencesFormal=0..1, occurencesText=Optional, cardinalityFormal=null, cardinalityText=null, subCardinalityFormal=null, subCardinalityText=null, dataType=DV_CODED_TEXT, bindings=null, values=
  • Low [Predominant intensity of staining is low.]
  • Intermediate [Predominant intensity of staining is intermediate.]
  • High [Predominant intensity of staining is high.]
, extendedValues=null], ResourceSimplifiedHierarchyItem [path=/items[at0094]/items[at0103], code=at0103, itemType=CLUSTER, level=2, text=Human Oestrogen receptor 2 assay (HER2), description=Human Oestrogen receptor 2 (HER2) assay., comment=null, uncommonOntologyItems=null, occurencesFormal=0..1, occurencesText=Optional, cardinalityFormal=1..*, cardinalityText=, subCardinalityFormal=null, subCardinalityText=null, dataType=CLUSTER, bindings=null, values=, extendedValues=null], ResourceSimplifiedHierarchyItem [path=/items[at0094]/items[at0103]/items[at0143], code=at0143, itemType=CLUSTER, level=3, text=Immunohistochemistry, description=HER2 Immunohistochemistry result., comment=null, uncommonOntologyItems=null, occurencesFormal=0..1, occurencesText=Optional, cardinalityFormal=1..*, cardinalityText=, subCardinalityFormal=null, subCardinalityText=null, dataType=CLUSTER, bindings=null, values=, extendedValues=null], ResourceSimplifiedHierarchyItem [path=/items[at0094]/items[at0103]/items[at0143]/items[at0107], code=at0107, itemType=ELEMENT, level=4, text=Immunohistochemistry score, description=HER2 immunohistochemistry score., comment=null, uncommonOntologyItems=null, occurencesFormal=0..1, occurencesText=Optional, cardinalityFormal=null, cardinalityText=null, subCardinalityFormal=null, subCardinalityText=null, dataType=DV_COUNT, bindings=null, values=min: >=0

, extendedValues=null], ResourceSimplifiedHierarchyItem [path=/items[at0094]/items[at0103]/items[at0143]/items[at0142], code=at0142, itemType=ELEMENT, level=4, text=Immunohistochemistry result, description=HER2 Immunohistochemistry result., comment=null, uncommonOntologyItems=null, occurencesFormal=0..1, occurencesText=Optional, cardinalityFormal=null, cardinalityText=null, subCardinalityFormal=null, subCardinalityText=null, dataType=DV_CODED_TEXT, bindings=null, values=
  • Positive [The HER2 Immunohistochemistry result is positive.]
  • Negative [The HER2 Immunohistochemistry result is negative.]
  • Equivocal [The HER2 Immunohistochemistry result is equivocal.]
, extendedValues=null], ResourceSimplifiedHierarchyItem [path=/items[at0094]/items[at0103]/items[at0144], code=at0144, itemType=CLUSTER, level=3, text=In situ hybridisation (ISH), description=HER2 In situ hybridisation (ISH)., comment=null, uncommonOntologyItems=null, occurencesFormal=0..1, occurencesText=Optional, cardinalityFormal=1..*, cardinalityText=, subCardinalityFormal=null, subCardinalityText=null, dataType=CLUSTER, bindings=null, values=, extendedValues=null], ResourceSimplifiedHierarchyItem [path=/items[at0094]/items[at0103]/items[at0144]/items[at0108], code=at0108, itemType=ELEMENT, level=4, text=ISH result, description=HER2 In situ hybridisation (ISH) result., comment=null, uncommonOntologyItems=null, occurencesFormal=0..1, occurencesText=Optional, cardinalityFormal=null, cardinalityText=null, subCardinalityFormal=null, subCardinalityText=null, dataType=DV_CODED_TEXT, bindings=null, values=
  • Positive [The HER2 In situ hybridisation (ISH) result is positive.]
  • Negative [The HER2 In situ hybridisation (ISH) result is negative.]
  • Equivocal [The HER2 In situ hybridisation (ISH) result is equivocal.]
, extendedValues=null], ResourceSimplifiedHierarchyItem [path=/items[at0094]/items[at0103]/items[at0144]/items[at0145], code=at0145, itemType=ELEMENT, level=4, text=Comment, description=A text comment on HER2 In situ hybridisation (ISH) result., comment=null, uncommonOntologyItems=null, occurencesFormal=0..1, occurencesText=Optional, cardinalityFormal=null, cardinalityText=null, subCardinalityFormal=null, subCardinalityText=null, dataType=DV_TEXT, bindings=null, values=, extendedValues=null], ResourceSimplifiedHierarchyItem [path=/items[at0030], code=at0030, itemType=CLUSTER, level=1, text=Lymph node involvement, description=Findings related to the involvement of tumour in lymph nodes., comment=null, uncommonOntologyItems=null, occurencesFormal=0..1, occurencesText=Optional, cardinalityFormal=1..*, cardinalityText=, subCardinalityFormal=null, subCardinalityText=null, dataType=CLUSTER, bindings=null, values=, extendedValues=null], ResourceSimplifiedHierarchyItem [path=/items[at0030]/items[at0087], code=at0087, itemType=SLOT, level=2, text=Sentinel nodes, description=Details of the involvement of tumour in sentinel lymph nodes., comment=null, uncommonOntologyItems=null, occurencesFormal=0..1, occurencesText=Optional, cardinalityFormal=null, cardinalityText=null, subCardinalityFormal=null, subCardinalityText=null, dataType=CLUSTER, bindings=null, values=Include:
openEHR-EHR-CLUSTER.lymph_node_metastases.v1
Exclude:
All not explicitly included archetypes, extendedValues=null], ResourceSimplifiedHierarchyItem [path=/items[at0030]/items[at0088], code=at0088, itemType=SLOT, level=2, text=Axillary nodes, description=Details of the involvement of tumour in axillary lymph nodes., comment=null, uncommonOntologyItems=null, occurencesFormal=0..1, occurencesText=Optional, cardinalityFormal=null, cardinalityText=null, subCardinalityFormal=null, subCardinalityText=null, dataType=CLUSTER, bindings=null, values=Include:
openEHR-EHR-CLUSTER.lymph_node_metastases.v1
Exclude:
All not explicitly included archetypes, extendedValues=null], ResourceSimplifiedHierarchyItem [path=/items[at0180], code=at0180, itemType=CLUSTER, level=1, text=Non-neoplastic changes, description=Findings of non-neoplastic change., comment=null, uncommonOntologyItems=null, occurencesFormal=0..1, occurencesText=Optional, cardinalityFormal=1..*, cardinalityText=, subCardinalityFormal=null, subCardinalityText=null, dataType=CLUSTER, bindings=null, values=, extendedValues=null], ResourceSimplifiedHierarchyItem [path=/items[at0180]/items[at0181], code=at0181, itemType=ELEMENT, level=2, text=Non-neoplastic change, description=Finding of non-neoplastic change., comment=null, uncommonOntologyItems=null, occurencesFormal=0..*, occurencesText=Optional, repeating, cardinalityFormal=null, cardinalityText=null, subCardinalityFormal=null, subCardinalityText=null, dataType=DV_CODED_TEXT, bindings=null, values=
  • Columnar cell changes [Columnar cell changes are present.]
  • Intraductal papilloma [Intraductal papilloma is present.]
  • Radial scars [Radial scars are present.]
  • Atypical ductal hyperplasia (ADH) [Atypical ductal hyperplasia (ADH) is present.]
  • Absent [Non-neoplastic change is absent.]
  • Indeterminate [Presence of non-neoplastic changes has not been determined.]
, extendedValues=null]], contacts=[], target=[], relationships=[], description=[], ism_transition=[], content=[], details=[], other_participations=[], data=[], provider=[]}, topLevelItems={items=ResourceSimplifiedHierarchyItem [path=ROOT_/, code=at0000, itemType=CLUSTER, level=0, text=null, description=null, comment=null, uncommonOntologyItems=null, occurencesFormal=1..1, occurencesText=Mandatory, cardinalityFormal=1..*, cardinalityText=, subCardinalityFormal=null, subCardinalityText=null, dataType=CLUSTER, bindings=null, values=null, extendedValues=null]}, addHierarchyItemsTo=items, currentHierarchyItemsForAdding=[ResourceSimplifiedHierarchyItem [path=/items[at0033], code=at0033, itemType=CLUSTER, level=1, text=Tumour size and extent, description=Assessments of tumour size., comment=null, uncommonOntologyItems=null, occurencesFormal=0..*, occurencesText=Optional, repeating, cardinalityFormal=1..*, cardinalityText=, subCardinalityFormal=null, subCardinalityText=null, dataType=CLUSTER, bindings=null, values=, extendedValues=null], ResourceSimplifiedHierarchyItem [path=/items[at0033]/items[at0036], code=at0036, itemType=SLOT, level=2, text=Invasive tumour extent, description=The size of the invasive aspect of the breast cancer., comment=null, uncommonOntologyItems=null, occurencesFormal=0..*, occurencesText=Optional, repeating, cardinalityFormal=null, cardinalityText=null, subCardinalityFormal=null, subCardinalityText=null, dataType=CLUSTER, bindings=null, values=Include:
openEHR-EHR-CLUSTER.physical_properties.v1
Exclude:
All not explicitly included archetypes, extendedValues=null], ResourceSimplifiedHierarchyItem [path=/items[at0033]/items[at0037], code=at0037, itemType=SLOT, level=2, text=Total lesion extent, description=The extent of total breast cancer lesion., comment=null, uncommonOntologyItems=null, occurencesFormal=0..*, occurencesText=Optional, repeating, cardinalityFormal=null, cardinalityText=null, subCardinalityFormal=null, subCardinalityText=null, dataType=CLUSTER, bindings=null, values=Include:
openEHR-EHR-CLUSTER.physical_properties.v1
Exclude:
All not explicitly included archetypes, extendedValues=null], ResourceSimplifiedHierarchyItem [path=/items[at0015], code=at0015, itemType=CLUSTER, level=1, text=Histologic grading, description=Histologic grading of breast cancer., comment=null, uncommonOntologyItems=null, occurencesFormal=0..1, occurencesText=Optional, cardinalityFormal=1..*, cardinalityText=, subCardinalityFormal=null, subCardinalityText=null, dataType=CLUSTER, bindings=null, values=, extendedValues=null], ResourceSimplifiedHierarchyItem [path=/items[at0015]/items[at0020], code=at0020, itemType=CLUSTER, level=2, text=Bloom and Richardson Grade, description=Bloom and Richardson Histology Grade ( with modification by Elston and Ellis) is composed of three components which are combined to produce a calculated Histology Grade., comment=null, uncommonOntologyItems=null, occurencesFormal=0..1, occurencesText=Optional, cardinalityFormal=1..*, cardinalityText=, subCardinalityFormal=null, subCardinalityText=null, dataType=CLUSTER, bindings=null, values=, extendedValues=null], ResourceSimplifiedHierarchyItem [path=/items[at0015]/items[at0020]/items[at0014], code=at0014, itemType=ELEMENT, level=3, text=Mitosis count, description=Mitotic frequency is calculated from the number of mitoses per 10 high-power fields., comment=null, uncommonOntologyItems=null, occurencesFormal=0..1, occurencesText=Optional, cardinalityFormal=null, cardinalityText=null, subCardinalityFormal=null, subCardinalityText=null, dataType=DV_COUNT, bindings=null, values=, extendedValues=null], ResourceSimplifiedHierarchyItem [path=/items[at0015]/items[at0020]/items[at0175], code=at0175, itemType=ELEMENT, level=3, text=Mitotic frequency score, description=Mitotic frequency score calculated from the mitosis count and the microscopy field diameter via a lookup table., comment=null, uncommonOntologyItems=null, occurencesFormal=0..1, occurencesText=Optional, cardinalityFormal=null, cardinalityText=null, subCardinalityFormal=null, subCardinalityText=null, dataType=C_DV_ORDINAL, bindings=null, values=1: Score 1 [Low mitotic frequency.]
2: Score 2 [Intermediate mitotic frequency.]
3: Score 3 [High mitotic frequency.]
, extendedValues=null], ResourceSimplifiedHierarchyItem [path=/items[at0015]/items[at0020]/items[at0016], code=at0016, itemType=ELEMENT, level=3, text=Nuclear score, description=Nuclear score., comment=null, uncommonOntologyItems=null, occurencesFormal=0..1, occurencesText=Optional, cardinalityFormal=null, cardinalityText=null, subCardinalityFormal=null, subCardinalityText=null, dataType=C_DV_ORDINAL, bindings=null, values=1: Score 1 [Size equivalent to 1.5–2 red blood cell diameters or normal duct epithelial nuclei; Diffuse chromatin; Inconspicuous nucleoli.]
2: Score 2 [Size equivalent to 2–2.5 red blood cell diameters; Coarse chromatin; Infrequent nucleoli and mitoses.]
3: Score 3 [Size > 2.5 red blood cell diameters; Pleomorphic vesicular nuclei; One or more prominent nucleoli; Frequent mitotic figures commonly present.]
, extendedValues=null], ResourceSimplifiedHierarchyItem [path=/items[at0015]/items[at0020]/items[at0017], code=at0017, itemType=ELEMENT, level=3, text=Tubular formation score, description=Tubular formation score, representing the extent of tubular formation within invasive carcinoma cells., comment=null, uncommonOntologyItems=null, occurencesFormal=0..1, occurencesText=Optional, cardinalityFormal=null, cardinalityText=null, subCardinalityFormal=null, subCardinalityText=null, dataType=C_DV_ORDINAL, bindings=null, values=1: Tubular formation score 1 [> 75% of invasive carcinoma forming tubular or glandular structures.]
2: Tubular formation score 2 [10–75% of invasive carcinoma forming tubular or glandular structures.]
3: Tubular formation score 3 [< 10% of invasive carcinoma forming tubular or glandular structures.]
, extendedValues=null], ResourceSimplifiedHierarchyItem [path=/items[at0015]/items[at0020]/items[at0018], code=at0018, itemType=ELEMENT, level=3, text=Histologic grade, description=Bloom and Richardson Grade of breast cancer, derived from the total score of its components: Mitotic frequency score, Nuclear score and Tubular formation score;, comment=null, uncommonOntologyItems=null, occurencesFormal=0..1, occurencesText=Optional, cardinalityFormal=null, cardinalityText=null, subCardinalityFormal=null, subCardinalityText=null, dataType=C_DV_ORDINAL, bindings=null, values=1: Grade 1 [Total score of 3–5.]
2: Grade 2 [Total score of 6 or 7.]
3: Grade 3 [Total score of 8 or 9.]
, extendedValues=null], ResourceSimplifiedHierarchyItem [path=/items[at0015]/items[at0020]/items[at0043], code=at0043, itemType=ELEMENT, level=3, text=Confounding issues, description=A text description of any assessment issues which may confound the accuracy of the Bloom and Richardson histologic grade., comment=null, uncommonOntologyItems=null, occurencesFormal=0..1, occurencesText=Optional, cardinalityFormal=null, cardinalityText=null, subCardinalityFormal=null, subCardinalityText=null, dataType=DV_TEXT, bindings=null, values=, extendedValues=null], ResourceSimplifiedHierarchyItem [path=/items[at0161], code=at0161, itemType=CLUSTER, level=1, text=Local tumour invasion, description=Findings of local tumour invasion., comment=null, uncommonOntologyItems=null, occurencesFormal=0..1, occurencesText=Optional, cardinalityFormal=1..*, cardinalityText=, subCardinalityFormal=null, subCardinalityText=null, dataType=CLUSTER, bindings=null, values=, extendedValues=null], ResourceSimplifiedHierarchyItem [path=/items[at0161]/items[at0159], code=at0159, itemType=SLOT, level=2, text=Lymphovascular invasion, description=Details of local invasion into lymphovascular tissue., comment=null, uncommonOntologyItems=null, occurencesFormal=0..1, occurencesText=Optional, cardinalityFormal=null, cardinalityText=null, subCardinalityFormal=null, subCardinalityText=null, dataType=CLUSTER, bindings=null, values=Include:
All not explicitly excluded archetypes
Exclude:
openEHR-EHR-CLUSTER.tumour_invasion.v1, extendedValues=null], ResourceSimplifiedHierarchyItem [path=/items[at0161]/items[at0160], code=at0160, itemType=SLOT, level=2, text=Skin / muscle invasion, description=Details of local invasion into skin or muscle tissue., comment=null, uncommonOntologyItems=null, occurencesFormal=0..1, occurencesText=Optional, cardinalityFormal=null, cardinalityText=null, subCardinalityFormal=null, subCardinalityText=null, dataType=CLUSTER, bindings=null, values=Include:
openEHR-EHR-CLUSTER.tumour_invasion.v1
Exclude:
All not explicitly included archetypes, extendedValues=null], ResourceSimplifiedHierarchyItem [path=/items[at0021], code=at0021, itemType=CLUSTER, level=1, text=Resection margins, description=Findings of the relation of tumour to surgical resection margins., comment=null, uncommonOntologyItems=null, occurencesFormal=0..1, occurencesText=Optional, cardinalityFormal=1..*, cardinalityText=, subCardinalityFormal=null, subCardinalityText=null, dataType=CLUSTER, bindings=null, values=, extendedValues=null], ResourceSimplifiedHierarchyItem [path=/items[at0021]/items[at0084], code=at0084, itemType=SLOT, level=2, text=Invasive carcinoma at margin, description=Details of invasive carcinoma at surgical resection margins., comment=null, uncommonOntologyItems=null, occurencesFormal=0..1, occurencesText=Optional, cardinalityFormal=null, cardinalityText=null, subCardinalityFormal=null, subCardinalityText=null, dataType=CLUSTER, bindings=null, values=Include:
openEHR-EHR-CLUSTER.tumour_resection_margins.v1
Exclude:
All not explicitly included archetypes, extendedValues=null], ResourceSimplifiedHierarchyItem [path=/items[at0021]/items[at0113], code=at0113, itemType=SLOT, level=2, text=DCIS at margin, description=Details of DCIS (Ductal carcinoma-in-situ) at surgical resection margins., comment=null, uncommonOntologyItems=null, occurencesFormal=0..1, occurencesText=Optional, cardinalityFormal=null, cardinalityText=null, subCardinalityFormal=null, subCardinalityText=null, dataType=CLUSTER, bindings=null, values=Include:
openEHR-EHR-CLUSTER.tumour_resection_margins.v1
Exclude:
All not explicitly included archetypes, extendedValues=null], ResourceSimplifiedHierarchyItem [path=/items[at0021]/items[at0115], code=at0115, itemType=SLOT, level=2, text=LCIS at margin, description=Details of LCIS (Local carcinoma-in-situ) at surgical resection margins., comment=null, uncommonOntologyItems=null, occurencesFormal=0..1, occurencesText=Optional, cardinalityFormal=null, cardinalityText=null, subCardinalityFormal=null, subCardinalityText=null, dataType=CLUSTER, bindings=null, values=Include:
openEHR-EHR-CLUSTER.tumour_resection_margins.v1
Exclude:
All not explicitly included archetypes, extendedValues=null], ResourceSimplifiedHierarchyItem [path=/items[at0054], code=at0054, itemType=CLUSTER, level=1, text=Non-neoplastic cellular changes, description=Findings of non-neoplastic cellular changes., comment=null, uncommonOntologyItems=null, occurencesFormal=0..1, occurencesText=Optional, cardinalityFormal=1..*, cardinalityText=, subCardinalityFormal=null, subCardinalityText=null, dataType=CLUSTER, bindings=null, values=, extendedValues=null], ResourceSimplifiedHierarchyItem [path=/items[at0054]/items[at0023], code=at0023, itemType=ELEMENT, level=2, text=Non-neoplastic cellular change, description=Finding of non-neoplastic cellular change., comment=null, uncommonOntologyItems=null, occurencesFormal=0..*, occurencesText=Optional, repeating, cardinalityFormal=null, cardinalityText=null, subCardinalityFormal=null, subCardinalityText=null, dataType=DV_TEXT, bindings=null, values=, extendedValues=null], ResourceSimplifiedHierarchyItem [path=/items[at0060], code=at0060, itemType=CLUSTER, level=1, text=Lobular neoplasia, description=Findings of lobular neoplasia and variants., comment=null, uncommonOntologyItems=null, occurencesFormal=0..1, occurencesText=Optional, cardinalityFormal=1..*, cardinalityText=, subCardinalityFormal=null, subCardinalityText=null, dataType=CLUSTER, bindings=null, values=, extendedValues=null], ResourceSimplifiedHierarchyItem [path=/items[at0060]/items[at0061], code=at0061, itemType=ELEMENT, level=2, text=Lobular neoplasia, description=Finding of lobular neoplasia., comment=null, uncommonOntologyItems=null, occurencesFormal=0..1, occurencesText=Optional, cardinalityFormal=null, cardinalityText=null, subCardinalityFormal=null, subCardinalityText=null, dataType=CHOICE, bindings=null, values=Choice of:
  •  Coded Text
    • Present - classical [Classical lobular neoplasia is present.]
    • Present - pleomorphic [Pleomorphic lobular neoplasia is present.]
    • Absent [Lobular neoplasia is absent.]
    • Indeterminate [The presence of lobular hyperplasia has not been determined.]
  •  Text
, extendedValues=null], ResourceSimplifiedHierarchyItem [path=/items[at0060]/items[at0055], code=at0055, itemType=ELEMENT, level=2, text=Atypical lobular hyperplasia, description=Finding of atypical lobular hyperplasia., comment=null, uncommonOntologyItems=null, occurencesFormal=0..1, occurencesText=Optional, cardinalityFormal=null, cardinalityText=null, subCardinalityFormal=null, subCardinalityText=null, dataType=CHOICE, bindings=null, values=Choice of:
  •  Coded Text
    • Present - classical [Classical atypical lobular neoplasia is present.]
    • Present - pleomorphic [Pleomorphic atypical lobular neoplasia is present.]
    • Absent [Atypical lobular neoplasia is absent.]
    • Indeterminate [The presence of atypical lobular neoplasia has not been determined.]
  •  Text
, extendedValues=null], ResourceSimplifiedHierarchyItem [path=/items[at0060]/items[at0058], code=at0058, itemType=ELEMENT, level=2, text=Lobular carcinoma-in-situ, description=Finding of lobular carcinoma-in-situ., comment=null, uncommonOntologyItems=null, occurencesFormal=0..1, occurencesText=Optional, cardinalityFormal=null, cardinalityText=null, subCardinalityFormal=null, subCardinalityText=null, dataType=CHOICE, bindings=null, values=Choice of:
  •  Coded Text
    • Present - classical [Classical lobular carcinoma-in-situ is present.]
    • Present - pleomorphic [Pleomorphic lobular carcinoma-in-situ is present.]
    • Absent [Lobular carcinoma-in-situ is absent.]
    • Indeterminate [The presence of lobular carcinoma-in-situ has not been determined]
  •  Text
, extendedValues=null], ResourceSimplifiedHierarchyItem [path=/items[at0060]/items[at0056], code=at0056, itemType=ELEMENT, level=2, text=Description, description=A text description of finding of lobular neoplasia., comment=null, uncommonOntologyItems=null, occurencesFormal=0..1, occurencesText=Optional, cardinalityFormal=null, cardinalityText=null, subCardinalityFormal=null, subCardinalityText=null, dataType=DV_TEXT, bindings=null, values=, extendedValues=null], ResourceSimplifiedHierarchyItem [path=/items[at0062], code=at0062, itemType=CLUSTER, level=1, text=Paget's disease of nipple, description=Findings related to Paget's disease of the nipple., comment=null, uncommonOntologyItems=null, occurencesFormal=0..1, occurencesText=Optional, cardinalityFormal=1..*, cardinalityText=, subCardinalityFormal=null, subCardinalityText=null, dataType=CLUSTER, bindings=null, values=, extendedValues=null], ResourceSimplifiedHierarchyItem [path=/items[at0062]/items[at0063], code=at0063, itemType=ELEMENT, level=2, text=Paget's disease of nipple, description=Finding of Paget's disease of the nipple., comment=null, uncommonOntologyItems=null, occurencesFormal=0..1, occurencesText=Optional, cardinalityFormal=null, cardinalityText=null, subCardinalityFormal=null, subCardinalityText=null, dataType=DV_CODED_TEXT, bindings=null, values=
  • Present [Paget's disease of the nipple is present.]
  • Absent [Paget's disease of the nipple is absent.]
  • Indeterminate [Presence of Paget's disease of the nipple has not been determined.]
, extendedValues=null], ResourceSimplifiedHierarchyItem [path=/items[at0024], code=at0024, itemType=CLUSTER, level=1, text=Microcalcification, description=Findings related to microcalcification., comment=null, uncommonOntologyItems=null, occurencesFormal=0..1, occurencesText=Optional, cardinalityFormal=1..*, cardinalityText=, subCardinalityFormal=null, subCardinalityText=null, dataType=CLUSTER, bindings=null, values=, extendedValues=null], ResourceSimplifiedHierarchyItem [path=/items[at0024]/items[at0025], code=at0025, itemType=ELEMENT, level=2, text=Microcalcification, description=Findings of microcalcification., comment=null, uncommonOntologyItems=null, occurencesFormal=0..1, occurencesText=Optional, cardinalityFormal=null, cardinalityText=null, subCardinalityFormal=null, subCardinalityText=null, dataType=DV_CODED_TEXT, bindings=null, values=
  • Present [Microcalcification is present.]
  • Absent [Microcalcification is absent.]
  • Indeterminate [Presence of microcalcification has not been determined.]
  • Present - no evidence of necrosis [Microcalcification is present with no evidence of necrosis.]
  • Present - with evidence of necrosis [Microcalcification is present with evidence of necrosis.]
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  • Present with necrosis [Calcification with necrosis is present in DCIS tissue.]
  • Present without necrosis [Calcification without necrosis is present in DCIS tissue]
  • Absent [Calcification is absent from DCIS tissue.]
  • Indeterminate [Presence of calcification in DCIS tissue has not been determined.]
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  • Present (non-comedo type) [Non-comedo type of tumour necrosis is present.]
  • Present (Comedo type) [Comedo type of tumour necrosis is present.]
  • Absent or minimal [Tumour necrosis is absent or minimal.]
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2: Score 2 [Size equivalent to 2–2.5 red blood cell diameters; Coarse chromatin; Infrequent nucleoli and mitoses.]
3: Score 3 [Size > 2.5 red blood cell diameters; Pleomorphic vesicular nuclei; One or more prominent nucleoli; Frequent mitotic figures commonly present.]
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2: Van Nuys Group 2 [Nuclear grade 1 or 2 and necrosis.]
3: Van Nuys Group 3 [Nuclear grade 3 with or without necrosis.]
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  •  Coded Text
    • Solid [Solid pattern of ductal carcinoma-in-situ.]
    • Cribriform [Cribriform pattern of ductal carcinoma-in-situ.]
    • Micropapillary [Micropapillary pattern of ductal carcinoma-in-situ.]
    • Apocrine [Apocrine pattern of ductal carcinoma-in-situ.]
    • Papillary [Papillary pattern of ductal carcinoma-in-situ.]
    • Indeterminate [The dominant pattern of ductal carcinoma-in-situ has not been determined.]
  •  Text
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  • Positive [Oestrogen Receptor assay result is positive.]
  • Negative [Oestrogen Receptor assay result is negative.]
  • Equivocal [Oestrogen Receptor assay result is equivocal.]
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  • Low [Predominant intensity of staining is low.]
  • Intermediate [Predominant intensity of staining is intermediate.]
  • High [Predominant intensity of staining is high.]
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  • Positive [Progesterone Receptor assay result is positive.]
  • Negative [Progesterone Receptor assay result is negative.]
  • Equivocal [Progesterone Receptor assay result is equivocal.]
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  • Low [Predominant intensity of staining is low.]
  • Intermediate [Predominant intensity of staining is intermediate.]
  • High [Predominant intensity of staining is high.]
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  • Positive [The HER2 Immunohistochemistry result is positive.]
  • Negative [The HER2 Immunohistochemistry result is negative.]
  • Equivocal [The HER2 Immunohistochemistry result is equivocal.]
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  • Positive [The HER2 In situ hybridisation (ISH) result is positive.]
  • Negative [The HER2 In situ hybridisation (ISH) result is negative.]
  • Equivocal [The HER2 In situ hybridisation (ISH) result is equivocal.]
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openEHR-EHR-CLUSTER.lymph_node_metastases.v1
Exclude:
All not explicitly included archetypes, extendedValues=null], ResourceSimplifiedHierarchyItem [path=/items[at0030]/items[at0088], code=at0088, itemType=SLOT, level=2, text=Axillary nodes, description=Details of the involvement of tumour in axillary lymph nodes., comment=null, uncommonOntologyItems=null, occurencesFormal=0..1, occurencesText=Optional, cardinalityFormal=null, cardinalityText=null, subCardinalityFormal=null, subCardinalityText=null, dataType=CLUSTER, bindings=null, values=Include:
openEHR-EHR-CLUSTER.lymph_node_metastases.v1
Exclude:
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  • Columnar cell changes [Columnar cell changes are present.]
  • Intraductal papilloma [Intraductal papilloma is present.]
  • Radial scars [Radial scars are present.]
  • Atypical ductal hyperplasia (ADH) [Atypical ductal hyperplasia (ADH) is present.]
  • Absent [Non-neoplastic change is absent.]
  • Indeterminate [Presence of non-neoplastic changes has not been determined.]
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