ARCHETYPE Insertion variant (openEHR-EHR-CLUSTER.insertion_variant.v0)

ARCHETYPE IDopenEHR-EHR-CLUSTER.insertion_variant.v0
ConceptInsertion variant
DescriptionA sequence change where, compared to the reference sequence, one or more nucleotides are inserted and where the insertion is not a copy of a sequence immediately 5'.
UseThis archetype should be used inside the "Variant" SLOT of the "Genetic variant" archetype.
PurposeTo describe an insertion variant observed in a sequence according to the HGVS nomenclature.
References"Den Dunnen et al. (2016) HGVS recommendations for the description of sequence variants: 2016 update. Hum.Mutat. 25: 37: 564-569"
Copyright© openEHR Foundation
AuthorsAuthor name: Cecilia Mascia
Organisation: CRS4, Italy
Email: cecilia.mascia@crs4.it
Date originally authored: 2017-02-23
Other Details LanguageAuthor name: Cecilia Mascia
Organisation: CRS4, Italy
Email: cecilia.mascia@crs4.it
Date originally authored: 2017-02-23
Other Details (Language Independent)
  • Licence: This work is licensed under the Creative Commons Attribution-ShareAlike 4.0 License. To view a copy of this license, visit http://creativecommons.org/licenses/by-sa/4.0/.
  • Custodian Organisation: Ocean Informatics
  • References: "Den Dunnen et al. (2016) HGVS recommendations for the description of sequence variants: 2016 update. Hum.Mutat. 25: 37: 564-569"
  • Original Namespace: com.oceaninformatics
  • Original Publisher: Ocean Informatics
  • Custodian Namespace: com.oceaninformatics
  • MD5-CAM-1.0.1: 89420BCB010A4619CE476F89645AB248
  • Build Uid: fa2b30f8-4525-485b-be9a-7bb0fccabd18
  • Revision: 0.0.1-alpha
Keywordsinsertion, variation, genetic, genomic, variant
Lifecyclein_development
UID2499e487-498d-4d3c-a8c7-eb8a0203f4ef
Language useden
Citeable Identifier1013.1.2344
Revision Number0.0.1-alpha
items
Start positionStart position: The position of the first of the two flanking nucleotides.
End positionEnd position: The position of the last of the two flanking nucleotides.
Inserted nucleotide(s)Inserted nucleotide(s): The sequence inserted between the two flanking nucleotides.
Reference sequenceReference sequence: The sequence file that has been used as a reference to describe the variant.
Include:
openEHR-EHR-CLUSTER.reference_sequence.v1 and specialisations
Other contributorsChristina Jaeger-Schmidt, Heidelberg University Hospital, Germany
Florian Kaercher, Charité Berlin, Germany
Francesca Frexia, CRS4, Italy
Gianluigi Zanetti, CRS4, Italy
Heather Leslie, Atomica Informatics, Australia (openEHR Editor)
Gideon Giacomelli, Charité Berlin, Germany
Paolo Uva, CRS4, Italy
Silje Ljosland Bakke, Nasjonal IKT HF, Norway (openEHR Editor)
Simon Schumacher, HiGHmed, Germany
Translators
  • German: Aurelie Tomczak, Institute of Pathology, University Hospital Heidelberg, Germany, au.tomczak@yahoo.com