ARCHETYPE Genetic copy number variant (openEHR-EHR-CLUSTER.copy_number_variant.v0)

ARCHETYPE IDopenEHR-EHR-CLUSTER.copy_number_variant.v0
ConceptGenetic copy number variant
DescriptionDescribes a copy number variant, where any part of a genome was deleted or duplicated (gain or loss of an allele).
UseUse to record the findings for a copy number variant observed in a genetic sequence. This archetype has been specifically designed to be used in the 'Variant' SLOT within the CLUSTER.genetic_variant archetype, but can also be used within other ENTRY or CLUSTER archetypes, where clinically appropriate.
PurposeTo record the details about a copy number variant observed in a genetic sequence.
References
Copyright© openEHR Foundation
AuthorsAuthor name: Gideon Giacomelli
Organisation: Charité Berlin, Germany
Email: gideon.giacomelli@charite.de
Date originally authored: 2019-02-01
Other Details LanguageAuthor name: Gideon Giacomelli
Organisation: Charité Berlin, Germany
Email: gideon.giacomelli@charite.de
Date originally authored: 2019-02-01
Other Details (Language Independent)
  • Licence: This work is licensed under the Creative Commons Attribution-ShareAlike 4.0 License. To view a copy of this license, visit http://creativecommons.org/licenses/by-sa/4.0/.
  • Custodian Organisation: Ocean Informatics
  • Original Namespace: com.oceaninformatics
  • Original Publisher: Ocean Informatics
  • Custodian Namespace: com.oceaninformatics
  • MD5-CAM-1.0.1: 232DA0AEDC0BB59E6384EC1F16B85D90
  • Build Uid: 42f43904-e464-4987-85c0-7518fbe3b31e
  • Revision: 0.0.1-alpha
Keywords
Lifecyclein_development
UIDaef2cdc1-2a43-4224-a1a1-8c922edbb758
Language useden
Citeable Identifier1013.1.2339
Revision Number0.0.1-alpha
items
Start positionStart position: Start position on the given reference sequence.
Number should not be treated as an absolute more as an estimation.
End positionEnd position: End position on the given reference sequence.
Number should not be treated as an absolute more as an estimation.
Total copy numberTotal copy number: Number of appearance of the allele.
Copy number change typeCopy number change type: Any copy number variant results in a gain or loss of the region e.g. a loss could result that a hetergozygous locus becomes homozygous since one gene was deleted.
  • Gain [Copy number gain.]
    [LOINC(2.65)::LA14033-7]
  • Loss [Copy number loss.]
    [LOINC(2.65)::LA14034-5]
Reference sequenceReference sequence: Structured details about the reference sequence.
Should be a specific chromosome most of the time.
Include:
openEHR-EHR-CLUSTER.reference_sequence.v1 and specialisations
Other contributorsCecilia Mascia, CRS4, Italy
Christina Jaeger-Schmidt, Heidelberg University Hospital, Germany
Florian Kaercher, Charité Berlin, Germany
Francesca Frexia, CRS4, Italy
Gianluigi Zanetti, CRS4, Italy
Heather Leslie, Atomica Informatics, Australia (openEHR Editor)
Paolo Uva, CRS4, Italy
Silje Ljosland Bakke, Nasjonal IKT HF, Norway (openEHR Editor)
Simon Schumacher, HiGHmed, Germany
Translators
  • German: Aurelie Tomczak, Institute of Pathology, University Hospital Heidelberg, Germany, au.tomczak@yahoo.com
  • Norwegian Bokmal: Liv Laugen, ​Oslo University Hospital, Norway, liv.laugen@ous-hf.no